Real time measurement of applied coatings in roll-to-roll applications is critical to improving the overall quality of the end product and process efficiency. Conventional inline measurement tools fall short as an accurate in-process measurement option as applied coatings become thinner. As a result, manufacturers face significant challenges in applying and verifying the correct amount of applied coatings. The availability of new high speed non-contact measurement alternatives that accurately measure the thickness or coat weight of thin films and oxide layers in roll-to-roll applications will improve accuracy, minimize process control issues and reduce costs by minimizing over application. The presented measurement technique is actively being used to precisely measure real time thickness of wet and dry applied coatings in the sub-micron range. Measurement data and summary results will be presented on numerous R2R coating applications, including a review of the repeatability, stability and accuracy of the measurement method.